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Admixture f3 representing modern Koreans and Japanese as a mixture of two populations, X and Y, color-coded by regions as in Fig. Error bars represent 1 SE. Phenotypes of interest The low coverage of our sample does not allow for direct observation of most SNPs linked to phenotypic traits of interest, but imputation based on modern-day populations can provide some information. We focused on the genome with highest coverage, DevilsGate1, using the same imputation approach that has previously been used to estimate genotype probabilities GPs for ancient European samples 5 , 16 , Thus, at least with regard to those phenotypic traits for which the genetic basis is known, there also seems to have been some degree of phenotypic continuity in this region for the last 7.
The cold climatic conditions in this area, where modern populations still rely on a number of hunter-gatherer-fisher practices, likely provide an explanation for the apparent continuity and lack of major genetic turnover by exogenous farming populations, as has been documented in the case of southeast and central Europe. Thus, it seems plausible that the local hunter-gatherers progressively added food-producing practices to their original lifestyle.
However, it is interesting to note that in Europe, even at very high latitudes, where similar subsistence practices were still important until very recent times, the Neolithic expansion left a significant genetic signature, albeit attenuated in modern populations, compared to the southern part of the continent. Our ancient genomes thus provide evidence for a qualitatively different population history during the Neolithic transition in East Asia compared to western Eurasia, suggesting stronger genetic continuity in the former region.
These results encourage further study of the East Asian Neolithic, which would greatly benefit from genetic data from early agriculturalists ideally, from areas near the origin of wet rice cultivation in southern East Asia , as well as higher-coverage hunter-gatherer samples from different regions to quantify population structure before intensive agriculture.
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